Clinical Studies – CSR3407 Methods and Results
This clinical study was double-blind, randomized , against placebo, done on two groups and was carried on 40 healthy female subjects from 50 to 70 y.o.during spring and for 12 weeks. The objective was to evaluate the anti-aging potential of oral intake 10g of naticol fish collagen peptides on cutaneous measures and its tolerance. 10g naticol was mixed with liquid and ingested in the morning. This study was conducted by CPCAD( independent pharmacology center specialized in dermatology from nice , France) and biomechanical measurements volunteers were controlled by certified dermatologist.
This clinical study was performed according to French regulatory competent authority (Ansm) and approved by the local Ethical committee (CPP). Consent was obtained from each subject before entry in the study.
Hydration – cornemeter CM825
This device measures the electrical Capactance of the skin which is expressed as an index of hydration. It allows to assess the hydration state of the first layers using electrical capacitance measurements.
Elasticity- Cutometer SEM 575
This method measures the degree of deformation and the time required For the skin to required for the skin to return to its original state. The deformation induced on the skin is measured by an optical system.The measured parameters are: Ue:the elastic deformation, ur: the elastic back deformation, uf: the total extensibility of the skin , ua: the total deformation recovery , ur/ue: the pure elasticity